Full names and holdings of significant shareholders expressed as a percentage of the issued share capital, as at 29th  March 201.

Shareholder No of Shares Percentage
Investec Wealth & Investment 47,724,071

28.75%

Woodford Investment Mgt 8,420,000 5.0%
Hawksmoor Investment Mgt 7,949,440 4.7%
Premier Fund Mgt 7,850,000 4.7%
Rathbone Investment Mgt 7,476,050 4.5%
Mr Simon Hope 6,845,966 4.1%
Charles Stanley 6,711,790 4.0%
Mr Stephen Barrow 6,430,562 3.8%
Hargreaves Lansdown Asset Mgt 5,776,524 3.4%
Columbia Threadneedle Investments 4,925,932 2.9%